Table 1:
Summary of Fold Change and Z’ Value of Four Different Receptors Known to Couple with Different G Protein Pathways, Measured by Individual Luciferase Reporter Assays
Luciferase Reporter
Receptor
G-protein subunit
Fold change
Z’ in 384-well
CRE-
luc2P
DRD
1
Gα
s
366
0.78
NFAT-RE-
luc2P
M
3
R
Gα
q
49
0.79
SRE-
luc2CP
M
4
R
Gα
i
11
0.85
SRF-RE-
luc2P
EDG receptor
Gα
12
127
0.83