A
Family |
Kinase |
Kinase concentration (nM) |
polyGT |
polyGAT |
CDK1 |
IRS1 |
JAK1 |
ABL |
ABL |
0.25 |
13.1 |
11.1 |
1.3 |
1.1 |
1.2 |
ABL |
ABL [T315I] (ABL1) |
0.5 |
6.6 |
6.4 |
1.3 |
1.2 |
1.3 |
ACK |
ACK |
20 |
27.3 |
27.2 |
4.8 |
1.5 |
2.0 |
ABL |
ARG |
0.5 |
13.2 |
12.7 |
1.4 |
1.2 |
1.4 |
SRC |
BLK |
0.5 |
16.5 |
7.8 |
9.6 |
1.1 |
2.6 |
TEC |
BMX |
0.5 |
13.2 |
9.0 |
2.2 |
1.1 |
1.2 |
FRK |
BRK |
3 |
17.4 |
3.0 |
1.4 |
1.3 |
1.1 |
TEC |
BTK |
0.25 |
11.8 |
19.6 |
3.1 |
1.0 |
1.5 |
CSK |
CSK |
20 |
10.4 |
20.3 |
1.7 |
1.3 |
3.9 |
CSK |
CTK |
20 |
12.6 |
18.8 |
1.0 |
1.0 |
1.0 |
FAK |
FAK |
3 |
20 |
13 |
1.0 |
1.0 |
1.0 |
FES |
FER |
0.25 |
12.9 |
17.1 |
16.1 |
9.1 |
5.8 |
FES |
FES |
1 |
17.1 |
19 |
10.3 |
7.2 |
4.0 |
SRC |
FGR |
0.1 |
25.1 |
17.7 |
4.1 |
1.1 |
3.2 |
FRK |
FRK |
0.5 |
20.8 |
22.9 |
1.3 |
1.1 |
2.2 |
SRC |
FYN |
0.25 |
12.8 |
10.4 |
19.7 |
1.0 |
2.3 |
SRC |
HCK |
0.25 |
21.3 |
13.2 |
12.8 |
1.2 |
5.1 |
TEC |
ITK |
0.5 |
9.8 |
8.5 |
2.5 |
1.6 |
1.6 |
JAK |
JAK1 |
7 |
17.6 |
16.4 |
1.3 |
3.7 |
19.5 |
JAK |
JAK2 |
1 |
8.9 |
7.9 |
7.2 |
21.4 |
41.8 |
JAK |
JAK3 |
0.5 |
6.7 |
6.9 |
1.3 |
6.0 |
37.3 |
SRC |
LCK |
0.5 |
10.4 |
16.5 |
6.1 |
1.0 |
1.7 |
SRC |
LYNa |
0.5 |
15.6 |
8.9 |
14.3 |
1.1 |
7.4 |
SRC |
LYNb |
1 |
18.6 |
13.2 |
24 |
1.2 |
18.3 |
FAK |
PYK2 |
0.25 |
15.5 |
7.7 |
2.3 |
1.1 |
1.3 |
SRC |
SRC |
0.5 |
15.1 |
18.4 |
16.6 |
1.1 |
5.9 |
FRK |
SRM |
0.5 |
18.3 |
20.1 |
8.0 |
1.3 |
2.0 |
SYK |
SYK |
0.5 |
2.3 |
4.1 |
1.2 |
1.8 |
20 |
TEC |
TEC |
0.5 |
25.4 |
15.4 |
2.2 |
1.0 |
1.8 |
ACK |
TNK1 |
1 |
9.3 |
15.2 |
2.4 |
1.6 |
1.2 |
TEC |
TXK |
3 |
11 |
18.9 |
3.2 |
1.2 |
1.3 |
JAK |
TYK2 |
4 |
6.2 |
5.3 |
1.3 |
7.3 |
15.2 |
SRC |
YES |
0.25 |
15.3 |
14 |
12.8 |
1.0 |
3.0 |
SYK |
ZAP70 |
4 |
11.1 |
15.3 |
1.1 |
1.1 |
6.7 |