| Systolic Blood Pressure (mmHg) | ||||||
|---|---|---|---|---|---|---|
| Groups SHR | Zero minute | 15 minutes | 30 minutes | 60 minutes | 120 minutes | 240 minutes |
| Control (n=12) | 185.2 ± 2.6 | 185.0 ± 1.8 | 185.5 ± 2.5 | 185.9 ± 1.8 | 186.1 ± 3.4 | 183.4 ± 2.8 |
| Losartan (n=11) | 178.2 ± 10.3 | 165.1 ± 6.9* | 164.2 ± 10.2* | 159.9 ± 11.6* | 144.2 ± 12.6* | 144.4 ± 11.1* |
| Captopril (n=12) | 183.6 ± 17.0 | 169.4 ± 15.7* | 167.7 ± 12.0* | 167.4 ± 11.8* | 166.8 ± 17.8* | 161.1 ± 17.4* |
| Compound 1 (n=12) | 195.1 ± 6.5 | 191.2 ± 5.0 | 191.3 ± 5.4 | 191.3 ± 6.1 | 191.1 ± 5.4 | 186.3 ± 5.7* |
| Compound 2 (n=12) | 177.3 ± 12.2 | 174.8 ± 16.2 | 182.6 ± 9.2 | 179.1 ± 9.9 | 178.7 ± 7.1 | 179.4 ± 8.5 |
| Compound 3 (n=12) | 179.1 ± 12.6 | 180.9 ± 13.6 | 179.0 ± 12.9 | 173.3 ± 17.4 | 173.4 ± 9.3 | 171.2 ± 6.2 |