Table 7: Lethal concentration (IC50) of the macrocyclic metal complexes on MCF-7 and Hep-G2 cell lines.
No |
Compound |
IC50(µg/mL)a
|
MCF-7 |
Hep-G2 |
1 |
[FeLCl2].1/2EtOH.1/2H2O |
2.5 |
3.0 |
2 |
[CoLCl (OH)]. H2O |
2.2 |
2.7 |
5 |
[NiLCl.H2O] Cl.H2O.1/2EtOH |
1.6 |
1.7 |
7 |
[CuLCl2].2H2O |
3.2 |
3.7 |
9 |
[CuL(OH)]NO3.H2O |
2.2 |
2.5 |
a : IC50 is the concentration of compound (in µg/mL) that inhibits a proliferation rate of the tumor cells by 50% as compared to control untreated cells.