Structure | Fungi | Concentrations (µg/mL) | MICa | IC50a | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
250 | 125 | 62.5 | 31.2 | 15.6 | 7.8 | 3.9 | 2 | 1 | 0.5 | ||||
Percentages of Inhibition (%) | |||||||||||||
Ca | 3.5 ± 0.8 |
1.0 ± 0.7 |
0.7 ± 0.1 |
0.6 ± 0.0 |
0.4 ± 0.1 |
0 | 0 | 0 | 0 | 0 | >250 | >250 | |
Cn | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | >250 | >250 | |
Ca | 53.1 ± 0.0 |
28.9 ± 1.3 |
15.8 ± 0.1 |
5.9 ± 0.6 |
4.5 ± 0.0 |
2.7 ± 0.2 |
2.3 ±0.4 |
0 | 0 | 0 | >250 | 250 | |
Cn | 65.9 ± 0.8 |
46.6 ± 0.5 |
15.8 ± 1.9 |
15.0 ± 0.2 |
9.7 ± 0.1 |
0 | 0 | 0 | 0 | 0 | >250 | 250 | |
Ca | 70.2 ± 0.1 |
18.1 ± 1.5 |
1.73 ± 1.8 |
0.6 ± 0.9 |
0 | 0 | 0 | 0 | 0 | 0 | >250 | 250 | |
Cn | 39.5 ± 0.8 |
12.6 ± 0.2 |
11.5 ± 0.2 |
9.8 ± 0.2 |
6.6 ± 0.2 |
6.4 ± 0.8 |
5.9 ± 0.2 |
0 | 0 | 0 | >250 | >250 | |
Ca | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 97.1 ± 0.0 |
68.9 ± 0.2 |
21.9 ± 0.8 |
3.9 | 1 | |
Cn | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 68.4 ± 0.5 |
31.1 ± 0.5 |
2 | 1 | |
Ca | 100 | 100 | 96.0 ± 1.1 |
33.0 ± 0.5 |
29.4 ± 0.1 |
5.1 ± 1.0 |
3.4 ± 0.4 |
0 | 0 | 0 | 125 | 62.5 | |
Cn | 93.1 ± 0.8 |
66.3 ± 2.0 |
30.1 ± 0.3 |
18.3 ± 0.9 |
9.4 ± 1.3 |
8.5 ± 1.0 |
8.1 ± 1.7 |
0 | 0 | 0 | >250 | 125 | |
Ca | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 32.4 ± 0.6 |
9.6 ± 0.1 |
0 | 3.9 | 3.9 | |
Cn | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 52.0 ± 1.6 |
35.7 ± 0.3 |
12.6 ± 1.0 |
3.9 | 1.9 | |
Ca | 100 | 100 | 100 | 100 | 100 | 100 | 85.7 ± 0.1 |
51.4 ± 1.0 |
27.5 ± 0.6 |
3.8 ± 0.7 |
7.8 | 2 | |
Cn | 100 | 100 | 100 | 100 | 65.4 ± 0.6 |
30.0 ± 0.3 |
11.5 ± 1.1 |
0 | 0 | 0 | 31.25 | 15.6 | |
Ca | 100 | 100 | 93.2 ± 0.2 |
51.8 ± 1.7 |
10.5 ± 1.1 |
3.4 ± 0.1 |
0.7 ± 0.7 |
0 | 0 | 0 | 125 | 31.25 | |
Cn | 100 | 100 | 97.4 ± 0.9 |
87.7 ± 0.2 |
49.3 ± 0.4 |
22.4 ± 2.2 |
7.8 ± 2.0 |
0 | 0 | 0 | 125 | 15.6 | |
Amphotericin B |
Ca Cn |
100 100 |
100 100 |
100 100 |
100 100 |
100 100 |
100 100 |
100 100 |
100 100 |
100 100 |
100 100 |
1.5 1.5 |
0.5 0.25 |