Table 2: Changes over time in measures of quality of life (The figure shows the groups in the time sequence of the cross-over design).

  Changes over time Between group differences over time Mean difference from 1st to 6th month Mean difference from 12th to 18th month

WHO-QoL
physical area

F(2.09, 3) = 4.67,
p = .01

F(2.09, 3) = 17.95, < .0001
Group A: – 2.7 (95% CI = – 3.7 to – 1.7)
Paired t = – 5.86, df = 17, p < .0001
Group A: 0.6 (95% CI = – 0.4 to 1.7)
Paired t = 1.21, df = 17, p = .24
Group B: 1.2 (95% CI = 0.5 to 1.8)
Paired t = 3.97, df = 19, p = .001
Group B: – 2.17 (95% CI = – 2.9 to – 1.3)
Paired t = – 5.72, df = 14, p < .0001

WHO-QoL
social area

F(2.40, 3) = 3.04,
p = .04

F(2.40, 3) = 15.65, < .0001
Group A: – 2.6 (95% CI = – 3.4 to – 1.8)
Paired t = – 7.21, df = 17, p < .0001
Group A: 0.8 (95% CI = – 0.6 to 2.2)
Paired t = 1.19, df = 17, p = .001
Group B: 2.2 (95% CI = 1.4 6 to 3.1)
Paired t = 5.75, df = 19, p < .0001
Group B: – 1.8 (95% CI = – 2.8 to – 0.9)
Paired t = – 4.36, df = 14, p = .001

WHO-QoL
psychological area

F(2.31, 3) = 4.67,
p = .05

F(2.31, 3) = 5.11, = .006
Group A: – 1.5 (95% CI = – 2.2 to – 0.8)
Paired t = – 4.60, df = 17, p < .0001
Group A: – 0.1 (95% CI = – 0.3 to 0.2)
Paired t = – 0.49, df = 17, p = .63
Group B: – 0.2 (95% CI = – 0.7 to 1.2)
Paired t = 0.52, df = 19, p = .60
Group B: – 0.5 (95% CI = – 1.2 to 0.2)
Paired t = – 1.51, df = 14, p = .15

WHO-QoL
environmental area

F(1.95, 3) = 4.35,
p = .01

F(1.95, 3) = 8.68, = .001
Group A: – 2.1 (95% CI = – 2.8 to – 1.3)
Paired t = – 5.61, df = 17, p < .0001
Group A: 0.7 (95% CI = – 0.1 to 1.5)
Paired t = 1.76, df = 17, p = .09
Group B: 0.4 (95% CI = 0.16 to 0.8)
Paired t = 2.34, df = 19, p = .03
Group B: – 0.5 (95% CI = – 1.1 to – 0.1)
Paired t = – 2.20, df = 14, p = .04

In group A patients were exposed to sailing from the 1st month to the 6th monthIn group B patients were exposed to sailing from the 12th month to the 18th month

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