| Baseline Characteristic |
Duloxetine(n=152)
|
SSRI (n=123) |
P-value |
| Age, Mean (SD) |
36.9 (7.9) |
37.7 (9.1) |
0.673 |
| Female, % |
28.3 |
42.3 |
0.015 |
| Caucasian, % |
83.6 |
86.2 |
0.547 |
| United Arab Emirates, % |
35.5 |
53.7 |
0.003 |
| Age at First Symptoms of MDD, Mean (SD) |
31.5 (7.3) |
31.3 (8.6) |
0.787 |
| BMI (kg/m2), Mean (SD) |
26.9 (4.2) |
26.5 (4.1) |
0.582 |
| Living with a Spouse, % |
77.0 |
76.4 |
0.838 |
| Independent Living, % |
13.8 |
15.4 |
0.703 |
| Level of Education, % |
- |
- |
0.013 |
| University or More |
63.8 |
50.4 |
- |
| Secondary School/Occupational Programme |
32.2 |
37.4 |
- |
| Primary School or Less |
3.9 |
12.2 |
- |
| CGI-S, Mean (SD) |
4.5 (0.6) |
4.5 (0.6) |
0.310 |
| QIDS-SR16, Mean (SD) |
12.6 (4.5) |
12.0 (4.9) |
0.234 |
| SSI-pain, Mean (SD) |
15.7 (4.9) |
14.7 (4.9) |
0.098 |
| Painful Physical Symptoms, % |
63.8 |
58.5 |
0.371 |
| Number of Comorbidities, % |
- |
- |
0.050 |
| None |
87.4 |
76.0 |
- |
| 1 |
11.3 |
21.5 |
- |
| ≥ 2 |
1.3 |
2.5 |
- |
| Had MDD Episodes in the Past 24 Months, % |
78.9 |
82.1 |
0.511 |
| Had been Hospitalised for MDD in the Past 24 Months, % |
2.6 |
6.5 |
0.118 |
| Had Taken Antidepressants in the Past 24 Months, % |
21.1 |
18.7 |
0.885 |
| Had Taken other Psychiatric Medications in the Past 24 Months, % |
- |
- |
0.001 |
| Benzodiazepines |
26.3 |
14.6 |
- |
| Other |
19.1 |
37.4 |
- |
| None |
54.6 |
48.0 |
- |
Abbreviations: BMI, Body Mass Index; CGI-S, Clinical Global Impressions of Severity; MDD, Major Depressive Disorder; QIDS-SR16, 16-item Quick Inventory of Depressive Symptomatology Self-Report; SD, Standard Deviation; SSI, Somatic Symptom Inventory; SSRI, Selective Serotonin Reuptake Inhibitor