Table 4: Parental burden and presence of significant depressive and anxiety symptoms by diagnostic group.

ASD DS T1DM Significant Between-group Differences *
Mothers Fathers Mothers Fathers Mothers Fathers
FPQ (mean item score ± SD)
Objective burden 1.9±0.7 1.8±0.7 1.6±0.6 1.5±0.5 1.5±0.5 1.4±0.3 ASD > DS > T1DM (all p<0.001)
for both mothers and fathers
Subjective burden 2.0±0.6 1.8±0.6 1.6±0.5 1.5±0.4 1.6±0.4 1.5±0.4 ASD > DS > T1DM (all p<0.001)
for both mothers and fathers
Adverse impact on other children under age 12 years 3.2±1.5 3.1±1.5 2.6±1.2 2.5±1.0 2.3±0.9 2.2±0.8 ASD > DS and T1DM (all p<0.01)
for both mothers and fathers
Adverse impact on parental work 2.8±1.0 2.7±1.1 2.5±0.7 2.4±0.9 2.3±0.6 2.1±0.5 Mothers: ASD > DS (p<0.05) and T1DM (p<0.01)
Fathers: ASD > DS (p<0.05) > T1DM (p<0.05)
Child health-related expenses (thousand euros, last year) 1.36±4.05 1.75±5.72 0.72±1.81 0.62±1.71 0.08±0.37 0.06±0.25 Mothers: ASD > T1DM (p<0.001)
Fathers: ASD > DS (p<0.05) and T1DM (p<0.01)
Time devoted to the child
(hours per week) (mean ± SD)
43.0±17.7 26.2±12.3 41.8±16.2 25.6±14.2 36.3±14.6 23.8±11.3 Mothers: T1DM < DS (p<0.01) and ASD (p<0.001)
Significant depressive and anxiety symptoms on the GHQ-12 (N, %) 113 (33.0) 85 (29.9) 29 (21.0) 16 (14.3) 40 (26.7) 31 (23.8) Fathers: ASD > DS (p<0.01)

ASD = Autism Spectrum Disorder; DS = Down’s syndrome; T1DM = Type 1 diabetes mellitus; FPQ = Family Problems Questionnaire; GHQ = General Health Questionnaire;
* after adjustment for age and for child’s age and sex