Fig. (3) Treatment response (%) reached at end-point (last follow-up visit) according to number of altered neuropshychological tests. We observed a gradual decline in the response rate, as the number of altered tests increased. The response rate (CGI) in patients with normal executive function (EF) evaluation was 76.4%, while the response rate for patients with 1 or 2 altered tests was 73.1% and 62.7% respectively. Note : NR: “no-response” PR= “partial response” CR = “complete response”.