Table 8: ROC area for VEGF-A and sorbitol tests (solo or combined) for diagnosing any type of DR by differentiating it from DNR.

ROC area p
Positive VEGF-A test (at optimum cut-off value of >=124.7 ng/ml) 0.766 <0.001
Positive Sorbitol test (at optimum cut-off value of >= 0.3112 mg/L) 0.777 <0.001
Parallel tests combination 0.768 <0.001
Serial tests combination 0.774 <0.001