Table 1: Spectrophotometric methods used for determination of thiocolchicoside alone and in combined dosage form.

Sr. No.	Name of drug	Sample matrix	Method		Detection (λ max) nm	Linearity range	Comments	Ref.
1	THC	Capsule	A	Zero order	259.0 nm	THC- 2.5 – 50 µg/mL	Simple and accurate	[13]
			B	First order	252.0 nm
			C	Second order	260.0 nm
			D	AUC	254.0 -264.0 nm
2	THC	Capsule	A	Zero order	259.8 nm		Simple and economical	[14]
			B	AUC	269.8-259.8 nm
3	THC	Capsule	Zero order		257.0 nm	THC-2-38 mg/mL	Simple	[15]
4	THC+DCF	Capsule	A	Q-value/Analysis	264 nm and 259 nm	THC- 2-40 µg/mL DCF- 1-50 µg/mL	Economic	[16]
			B	Simultaneous equation
5	THC+DCF	Tablets	A	Absorption correction	264.99 nm and 373.84 nm	DCF-25-75 µg/mL THC-4-12 µg/mL	Higher linearity range	[17]
			B	Area Under Curve (AUC)	DCF 252.56-260.59 nm and THC 278.51-285.53 nm
6	THC+DCF	Tablets	A	Ratio Derivative	268.78 and 355.62 nm	12.5-75 μg/m1	Different linearity and complex	[18]
			B	Dual Wavelength	252.47nm and 260.74 nm	25-75 μg/mL
7	THC+DCF	Capsule	Simultaneous equation		259 nm and 277nm	THC 4 - 24 µg/mL & DCF 10 - 60 µg/mL	Simple and economical	[19]
8	THC+DCF	Capsule	Multicomponent mode		254,259,265,271,286	THC-20-100µg/mL and DCF-20-100 µg/mL	Economical	[20]
9	THC+DCF	Capsule	A	Absorbance correction method	276.6 nm and 372.8 nm	DCF-5‐30 μg/mL and THC-10‐60μg/mL	Sensitive	[21]
			B	First order derivative	278.6 nm and 243.2 nm
			C	Dual wavelength	244nm and 269 nm
10	THC+DCF	Capsule	A	Simultaneous Equation method	260.0 nm THC and 276.5 nm DCF	THC-1-10 µg/mL and DCF-6.25-62.5 µg/mL	Easy and economical	[22]
			B	Absorbance Correction method	276.5 nm DCF, 373.0 nm is isoabsorptive point of THC
11	THC+ DCF	Capsule	A	absorption correction method	THC-397.80 nm and DCF- 271.0 nm	THC-5-35 µg/mL and 10-70 µg/mL	Accurate	[23]
12	THC+ ACE	Tablet	A	AUC	264.5-254.5 nm for THC and 279.0-269.0 nm for ACE	THC and DCF- 4-36 µg/mL	Precise and selective	[24]
13	THC+ ETD	Tablet	Absorbance Ratio Method		260 nm and 232nm	ETD-15-100µg/mL and THC-2-20µg/mL	Selective	[25]
14	THC+ DXKET	Tablet	Absorbance correction		370 nm and 255 nm	THC 4-40µg/mL and DKET 5-50µg/mL	Accurate and sensitive	[26]
			First order derivative		232 nm and 242 nm
15	THC+ KET	Tablet	First order derivative		THC 233.0 nm and KET 243.0 nm	THC- 3-15 µg/mL and KET-12-60 µg/mL	Simple and selective	[27]
			Absorbance correction		THC 372.0 nm, KET 260.0 nm.	THC-1-5µg/mL and KET- 10-50 µg/mL
16	PCM+ THC+ ACE	Tablet	Multicomponent mode		PCM-256 nm, THC 258 nm, ACE 270 nm.	PCM- 1-25 µg/mL, THC- 2.5-25 µg/mL and ACE- 1-25 µg/mL	Economical	[28]
17	PCM+ THC+ ACE	Tablet	Multicomponent mode		PCM 249 nm, THC 258 nm, ACE 276 nm.	PCM -5-25 µg/mL THC-1-5 µg/mL and ACE- 1-5 µg/mL	Economical	[29]
18	THC	Injection	Spectrofluorimetry		289 nm and 366 nm.	THC-1-10µg/mL	Specific	[30]