Formulations |
Amount of drug permeated in 4 hrs |
Permeation (%) | Corneal hydration level (%) | |
---|---|---|---|---|
(µg) | (mg) | |||
VOZOLE (1% w/v) | 20.747 ± 0.458 | 0.021 ± 0.001 | 2.075 ± 0.046 | 76.433 ± 0.188 |
OAVM-2 | 52.399 ± 0.813† | 0.052 ± 0.001 | 5.240 ± 0.081 | 79.270 ± 0.256 |
IPMVM-11 | 69.073 ± 0.667†† | 0.069 ± 0.001 | 6.907 ± 0.067 | 77.780 ± 0.699 |
IPPVM-17 | 47.310 ± 0.637† | 0.047 ±0.001 | 4.731 ± 0.064 | 77.213 ± 0.213 |