Table 5: Results of Placket-Burman experimental design showing observed and predicted responses of in vitro drug release study.

Formulation No. Factors to be screened    
  A B C D E F Observed response* Predicted response
F1 30 7:1 0.5 7.4 65 80 40.32±0.12 36.55
F2 30 1:1 1 7.4 65 60 41.92±0.72 40.53
F3 10 7:1 1 7.4 55 60 50.39 ±0.02 48.55
F4 30 7:1 1 6.8 55 60 51.51±0.40 51.35
F5 30 7:1 0.5 6.8 55 80 50.09±0.49 50.69
F6 30 1:1 0.5 6.8 65 60 40.30±0.28 42.43
F7 10 1:1 0.5 7.4 55 80 63.42±0.33 62.97
F8 10 1:1 1 6.8 65 80 35.62±0.06 37.73
F9 10 7:1 0.5 7.4 65 60 42.74±0.24 42.95
F10 30 1:1 1 7.4 55 80 44.98±0.25 45.47
F11 10 7:1 1 6.8 65 80 53.49±0.13 52.81
F12 10 1:1 0.5 6.8 55 60 52.98±0.23 53.77

*Averages of 3 determinations of obseved response (Mean ± SD)