Activity Class | Abbreviation | Biological Function | Number of Active Structures |
---|---|---|---|
5HT1A agonists | 5HT1A | Treatment of anxiety and depression | 827 |
5HT3 antagonists | 5HT3 | Treatment for nausea and vomiting | 752 |
5HT reuptake inhibitors | 5HT Reuptake | 359 | |
Angiotensin II AT1 antagonists | AT1 | Treatment for hypertension, diabetes nephropathy and cognitive heart failure | 943 |
Cyclo-oxygenase inhibitors | COX | Relief inflammation and pain | 636 |
D2 antagonists | D2 | Treatment for symptoms of schizophrenia | 395 |
HIV protease inhibitors | HIVP | Prevent viral replication | 750 |
Protein kinase C inhibitors | PKC | Regulate cell growth and transcription, mediate immune response and modulate membrane structure | 453 |
Renin inhibitors | Renin | Reduce blood pressure and treatment for hypertension | 1130 |
Substance P inhibitors | SubP | Associated with intense and chronic pain | 1246 |
Thrombin inhibitors | Thrombin | Delay blood clotting | 803 |