Activity Class | Fusion Order and Range (%) |
---|---|
Renin | ECFP4: R5 > R1 > R3 > R2 > R4 > FR (-6.11 - 5.07) ECFC4: R5 > R4 > R3 > R1 > FR > R2 (-7.95 - 0.74) SRECFC4: R2 > R1 > FR > R4 > R5 > R3 (-3.53 - 0.08) |
AT1 | ECFP4: R2 > FR > R5 > R3 > R4 > R1 (-2.07 - 1.18) ECFC4: R5 > R2 > R4 > R3 > R1 > FR (-11.03 - 0.47) SRECFC4: R4 > R2 > R3 > FR > R1 > R5 (3.97 - 6.41) |
HIVP | ECFP4: R1 > R4 > R2 > FR > R3 > R5 (10.39 - 29.13) ECFC4: R4 > R3 > R5 > R1 > R2 > FR (4.83 - 30.38) SRECFC4: R5 > R2 > R1 > R4 > R3 > FR (8.35 - 28.66) |
Thrombin | ECFP4: R1 > R5 > R4 > R2 > R3 > FR (4.81 - 31.06) ECFC4: R5 > R2 > R3 > R1 > R4 > FR (16.89 - 28.59) SRECFC4: R5 > R3 > R1 > R4 > R2 > FR (-10.70 - 14.34)) |
SubP | ECFP4: R3 > R1 > R4 > R5 > R2 > FR (-21.54 - 2.94) ECFC4: R3 > R4 > R1≈ R2 > R5 > FR (-10.23 - 4.77) SRECFC4: R3 > R1 > R4 > R5 > R2 > FR (-10.70 - 14.34) |
5HT3 | ECFP4: R3 > R1 > R5 > FR > R4 > R2 (-5.25 - 8.60) ECFC4: R3 > R4 > R2 > R1 > R5 > FR (6.14 - 31.45) SRECFC4: R3 > R1 > R5 > R4 > R2 > FR (-1.30 - 15.38) |
5HT Reuptake |
ECFP4: R1 > R3 > R4 > R5 > R2 > FR (14.96 - 31.77) ECFC4: R1 > R5 > R3 > R4 > R2 > FR (0.43 - 20.37) SRECFC4: R1 > R2 > R3 > R4 > FR > R5 (10.24 - 32.13) |
D2 | ECFP4: FR > R4 > R2 > R5 > R1 > R3 (9.16 - 29.73) ECFC4: R4 > R5 > R2 > R1 > R3 > FR (13.38 - 25.00) SRECFC4: R2 > FR > R1 > R5 > R1 > R3 (3.42 - 22.21) |
5HT1A | ECFP4: R4 > R3 > FR > R2 > R5 > R1 (3.93 to 12.25) ECFC4: R5 > R4 > R1 > FR > R2 > R3 (13.63 to 26.44) SRECFC4: R4 > R1 > R5 > R2 > FR > R1 (13.09 to 26.59) |
PKC | ECFP4: R3 > R5 > R4 > R2 > R1 > FR (6.67 - 45.86) ECFC4: R1 > R5 > R2 > FR > R3 > R4 (8.66 -17.76) SRECFC4: R2 > R4 > R3 > R1 > R5 > FR (11.88 - 22.77) |
COX | ECFP4: R1 > R5 > R4 > R3 > R2 > FR (15.56 - 30.93) ECFC4: R2 > R5 > R3 > R1 > R4 > FR (-8.06 - 6.63) SRECFC4: R5 > R2 > R3 > R1 > R4 > FR (9.16 - 50.32) |