Table 1: Composition of solid dispersion and evaluation of drug content, saturation solubility and cumulative drug release.

Sr. No Batch code Drug: Carrier Drug content
(%)
Saturation solubility
(mg/mL)
Cumulative drug release (%)
after 60 min
1 Pure drug -- -- 55.54±1.02 37.70±2.22
2 SD1 1:1 (PEG 4000) 95.77±1.48 88.72±1.63 73.28±1.21
3 SD2 1:3 (PEG 4000) 96.16±1.11 104.33±1.52 78.59±1.23
4 SD3 1:5 (PEG 4000) 99.23±0.86 123.63±1.73 92.25±1.35
5 SD4 1:1 (HPβ-CD) 95.39±0.78 110.24±1.99 82.75±1.45
6 SD5 1:3 (HPβ-CD) 95.43±0.43 138.16±1.69 90.25±1.54
7 SD6 1:5 (HPβ-CD) 99.58±1.18 174.23±1.36 95.11±1.22

Data represented as percent mean ±SD, n=3; p<0.01