Table 5: Toxicities reported as a reason for initial ART change at NGH from 2006 to 2016.

Toxicity Start Regimen in which Toxicity Occurred Responsible Medication Frequency Percentage (%)
Peripheral neuropathy D4T+3TC+NVP DT4 13 47.1%
D4T+3TC+EFV D4T 3
Severe rash AZT+3TC+NVP NVP 7 20.6%
Anemia AZT+3TC+NVP AZT 4 14.7%
AZT+3TC+EFV AZT 1
Hepatotoxicity AZT+3TC+NVP NVP 3 8.8%
CNS complication TDF+3TC+EFV EFV 2 5.9%
Nephrotoxicity TDF+3TC+EFV TDF 1 2.9%