Dendritic Cells in Autoimmune Diseases

Mouse DC subsets	CD8α⁺CD4^-	CD8α^-CD4^-	CD8α^-CD4⁺	CD8α^-CD4^-	‘Langerhans’ DCs CD8α^lowCD4^-	Plasmacytoid DCs
C-type lectins	DEC205^high	DEC205^-	DCIR	DEC205⁺	DEC205^high, Langerin	DEC205^-
Specific Molecules	CD8, CD11c^high,	CD11b, CD11c^high	CD4, CD11b, CD11c^high	CD11c^high	CD11b	CD11c^low, CD4^low , B220 (CD45R)

DCIR= Dendritic cell immunoreceptor. Markers that are useful for segregating mouse DC subtypes include CD11b and the interdigitating DC marker CD205 (the multilectin domain moleculeDEC205, originally known as NLDC-145). The upper table is reproduced from Immunol Rev 2007; 219: 118-142 (ref. [4]) with permission from Wiley-Blackwell.