Table 2: Self-assessment of Pain and Function in Patients with OA Before and Six months after Bone Marrow Prolotherapy

Patient No. (N = 24) No. of Treatments Pain * at Rest Pain ADL Pain on Exercise Degree of Stiffness Limitations in ROM Level of Crepitus
Before After Before After Before After Before After Before After Before After
Knee (Scale: 0-3. minimal; 4-6, moderate; 7-10, severe)
1 3 0 0 8 2 10 1 0 0 5 1 2 0
2a 3 7 2 7 2 9 2 8 2 6 2 7 2
4 5 4 0 4 0 5 0 3 6 0 0 0 0
5 5 4 0 4 0 5 0 3 0 6 0 0 0
8 1 10 0 10 0 10 0 5 0 6 0 6 0
10 3 10 0 10 0 10 0 10 0 10 0 10 0
11 3 10 0 10 0 10 0 10 0 10 0 10 0
12 2 5 0 7 0 9 1 8 1 7 0 6 0
13 2 5 0 7 0 9 1 8 1 7 0 6 0
14 5 6 0 3 0 2 0 0 0 0 0 6 0
15 4 0 0 1 0 0 0 0 0 0 0 3 0
23 3 6 2 6 2 6 2 8 1 8 1 7 1
24 3 6 2 6 2 6 2 8 1 8 1 7 1
Hip (Scale: 0-3. minimal; 4-6, moderate; 7-10, severe)
6 7 0 0 3 0 4 0 8 1 5 1 0 0
7 7 0 0 5 0 6 1 8 2 9 3 3 0
9 4 3 0 5 1 5 1 8 2 8 5 6 1
16 7 0 0 3 0 4 0 0 0 4 0 0 0
17 4 0 0 2 0 0 0 0 0 7 0 4 0
18 1 0 0 4 0 3 0 3 0 7 5 2 0
19 2 6 0 6 0 8 0 8 0 6 5 4 0
21 3 9 0 9 0 9 0 9 1 7 5 7 0
Other joint disease (Scale: 0-3. minimal; 4-6, moderate; 7-10, severe)
3b 4 7 0 9 0 10 0 9 1 9 1 0 0
20c 3 5 0 5 0 5 0 8 5 8 5 2 0
22d 3 7 0 7 0 7 0 7 2 7 2 0 0
Mean 3.63 4.58 0.25 5.88 0.38 6.33 0.46 6 0.83 6.46 1.54 4.08 0.21
SD 3.51 0.66 2.61 0.77 3.14 0.72 3.56 1.17 2.47 1.98 3.22 0.51
P Value = .05 P< .001 P< .001 P< .001 P< .001 P< .001 P< .001
Paired t test: t23 6.16 10.28 9.38 6.05 7.45 6.41
Abbreviations: ADL=activities of daily living; ROM=range of motion, SD = standard deviation.
* Pain level as rated by Visual Analog Pain Scale (VAS).
6 months or longer.
df.
a R knee, torn medial meniscus-post surgery.
b R ankle, avascular necrosis, osteoarthritis.
c L big toe, osteoarthritis with bone spurs.
d Lower back pain from degenerative disc disease.