| Time |
Ketamine (N=40) |
Control (N=40) |
P-value | Difference (Ket- Control) | |
|---|---|---|---|---|---|
| Mean± SE | 95% CI | ||||
| Base | 95.0±3.4 | 94.5±3.2 | 0.477 | 0.5±0.7 | -0.9–2.0 |
| Minute-5 | 94.3±6.0 | 51.7±11.3 | <0.001* | 42.6±2.0 | 38.6–46.6 |
| Minute-10 | 94.3±5.9 | 76.0±12.1 | <0.001* | 18.3±2.1 | 14.0–22.5 |
| Minute-15 | 94.2±5.8 | 85.8±12.5 | <0.001* | 8.5±2.2 | 4.1–12.8 |
| Minute-20 | 97.5±5.9 | 88.2±14.8 | 0.001* | 9.3±2.5 | 4.3–14.3 |
| Minute-35 | 98.3±5.9 | 94.9±14.7 | 0.181 | 3.4±2.5 | -1.6–8.4 |
| Minute-50 | 95.2±5.9 | 90.9±14.7 | 0.088 | 4.4±2.5 | -0.6–9.3 |
| Minute-65 | 95.1±5.9 | 93.6±14.8 | 0.555 | 1.5±2.5 | -3.5–6.5 |
| End | 95.2±5.8 | 93.7±14.6 | 0.556 | 1.5±2.5 | -3.5–6.4 |
| Ephedrine Dose (mg) | 0.9±2.2 | 26.3±5.3 | <0.001* | -25.4±0.9 | -27.1–-23.6 |