Fig. (1) Group A (saline N): Standard pharmacotherapy +normal saline 0.9% (5ml) nebulizer /8hr. Group B(H saline N): Standard pharmacotherapy + hypertonic saline 3% (5ml) nebulizer /8hr Group C(saline IV):Standard pharmacotherapy + normal saline 0.9% (500ml) intravenous /24hr Group D(H saline IV): Standard pharmacotherapy + hypertonic saline 3% (500ml) intravenous /24hr. Difference chart between groups according to the Murray score.