Study Groups (Mean ± SD) | P-values* | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Days |
A (saline N) |
B (H saline N) |
C (saline IV) |
D (H saline IV) |
A vs B | A vs C | A vs D | B vs C | B vs D | C vs D | Overall |
Day 0 | 3.1 ±0.72 | 3.2±0.74 | 3.47±0.63 | 3.0±0.69 | 0.094 | ||||||
Day 1 | 2.93±0.58 | 3.00±0.53 | 3.20±0.76 | 2.55±0.73 | 0.651 | 0.156 | 0.042* | 0.276 | 0.014* | 0.003* | 0.006* |
Day2 | 2.88±0.91 | 2.53±1.11 | 3.07±0.87 | 2.10±1.07 | 0.219 | 0.445 | 0.007* | 0.056 | 0.161 | <0.001 | 0.004* |
Day 3 | 2.33±1.27 | 2.1 ±1.10 | 2.67±0.88 | 1.80±1.06 | 0.488 | 0.267 | 0.108 | 0.044* | 0.321 | 0.002* | 0.035* |
Day 4 | 1.87±1.15 | 1.13±1.04 | 2.40±1.16 | 1.07±0.94 | 0.019* | 0.104 | 0.008* | <0.001 | 0.828 | <0.001 | <0.001 |
Day 5 | 1.67±1.08 | 0.73±1.01 | 1.53±1.17 | 1.00±0.89 | 0.002* | 0.655 | 0.018* | 0.011* | 0.311 | 0.072 | 0.004* |
Day 6 | 1.40±1.15 | 0.33±0.71 | 1.27±1.26 | 0.87±0.71 | <0.001 | 0.699 | 0.050* | <0.001 | 0.008* | 0.165 | <0.001 |
Day 7 | 0.87±0.90 | 0.27±0.58 | 0.73±0.87 | 0.67±0.69 | 0.006* | 0.571 | 0.372 | 0.029* | 0.028* | 0.784 | 0.039* |
Day 8 | 0.53±0.73 | 0.46±0.31 | 0.67±0.88 | 0.23±0.35 | 0.654 | 0.535 | 0.064 | 0.256 | 0.015* | 0.022* | 0.013* |
Day 9 | 0.33±0.61 | 0.27±0.17 | 0.40±0.72 | 0.16±0.41 | 0.082 | ||||||
Day 10 | 0.27±0.58 | 0.15±0.11 | 0.37±0.45 | 0.11±0.10 | 0.057 | ||||||
Day 11 | 0.13±0.51 | 0.00±0.00 | 0.00±0.00 | 0.00±0.00 | 0.096 | ||||||
Day 12 | 0.13±0.51 | 0.00±0.00 | 0.00±0.00 | 0.00±0.00 | 0.096 | ||||||
Day 13 | 0.00±0.00 | 0.00±0.00 | 0.00±0.00 | 0.00±0.00 | 1.000 | ||||||
Day 14 | 0.00±0.00 | 0.00±0.00 | 0.00±0.00 | 0.00±0.00 | 1.000 | ||||||
ICU Days | 9.60±4.10 | 6.87±2.85 | 10.13±3.56 | 7.07±4.21 | 0.007* | 0.620 | 0.033* | <0.001 | 0.841 | 0.006* | 0.002* |
Need for Mechanical Ventilation: Number (%)** | A vs B | A vs C | A vs D | B vs C | B vs D | C vs D | |||||
No need | 19 (73.1) | 10 (38.5) | 18 (69.2) | 10 (38.5) | 0.012* | 0.760 | 0.012* | 0.026* | 1.000 | 0.026* | |
Non-Inv. | 5 (19.2) | 3 (11.5) | 7 (26.9) | 6 (23.1) | 0.442 | 0.510 | 0.734 | 0.159 | 0.271 | 0.749 | |
Inv. | 14 (53.8) | 7 (26.9) | 11 (42.3) | 4 (15.4) | 0.048* | 0.405 | 0.004* | 0.244 | 0.308 | 0.032* |