Analgesic and Anti-Gastropathic Effects of Salidroside Isolated from Acer tegmentosum Heartwood

Table 1: Anti-Nociceptive Effect of the MeOH Extract of A. tegmentosum Heartwood and Its Fractions in Hot-Plate Test and Acetic Acid-Induced Writhing Syndrome in Mice

Group	Dose (mg/kg)	Stretching Episode (count/min)	Action Time (sec)
Control	-	66.4 ± 2.41^a	10.3 ± 3.17^g
MeOH extract	100	63.4 ± 2.70^ab	13.2 ± 2.96^defg
	200	56.6 ± 2.70^c	14.2 ± 1.33^cdefg
CHCl₃ fraction	100	63.4 ± 2.30^ab	11.9 ± 2.16f^g
	200	64.8 ± 3.77^ab	12.8 ± 1.92^efg
BuOH fraction	100	53.4 ± 2.70^cd	15.2 ± 2.41^cdef
	200	45.4 ± 2.88^e	17.9 ± 2.38^bc
H₂O fraction	100	56.2 ± 3.19^cd	14.6 ± 2.18^cdef
	200	52.6 ± 2.70^d	16.8 ± 2.06^bcde
Aspirin	100	16.2 ± 1.30^h	-
Morphine	10	-	28.5 ± 4.16^a

Samples were administered orally for one week and mice were tested one hour after the last treatment. Data are mean ± SD value (n = 9 mice per group). Values followed by superscripted letters are significantly different (p < 0.05) by Duncan's multiple range test.