Analgesic and Anti-Gastropathic Effects of Salidroside Isolated from Acer tegmentosum Heartwood

Table 2: Effect of the MeOH Extract of A. tegmentosum Heartwood and Its Fractions on HCl-Ethanol- and Indomethacin- Bethanechol-Induced Gastric Ulcers in Mice

Group	Dose	Ulcerative Index (mm)
	(mg/kg)	HCl-Ethanol	Indomethacin-Bethanechol
Control	-	27.4 ± 2.10^a	14.7 ± 0.93^a
MeOH extract	100	26.2 ± 3.12^abc	13.5 ± 0.45^bcd
	200	22.5 ± 4.25^bcd	11.2 ± 0.50^e
CHCl₃ fraction	100	28.9 ± 3.46^a	14.1 ± 0.72^abc
	200	26.5 ± 4.17^ab	13.2 ± 0.61^cd
BuOH fraction	100	21.7 ± 3.43^cd	10.8 ± 0.39^ef
	200	18.9 ± 2.11^d	9.4 ± 0.50^g
H₂O fraction	100	25.9 ± 1.43^d	12.9 ± 0.33^d
	200	20.6 ± 2.53^d	10.5 ± 0.41^ef
Cimetidine	100	2.36 ± 1.86^e	-
Omeprazol	100	-	5.62 ± 0.91^h

Samples were administered orally for two weeks before HCl/ethanol or indomethacin/bethanechol induction of gastric ulcers in mice. Data are mean ± SD value (n = 9 mice per group). Values followed by superscripted letters are significantly different (p < 0.05) by Duncan's multiple range test.