Fig. (3) The effects of ganoderic acid DM (1), methyl ganoderic acid DM (2) and 7-oxo-methyl ganoderic acid Z (3) on selectivity to inhibit the osteoclastogenesis.(◊:ganoderic acid DM (1), □: methyl ganoderic acid DM (2), ∆: 7-oxo-methyl ganoderic acid Z (3)) Results are given as the mean±S.D., n=4. ** P <0.01 vs vehicle control.