Table 1: Inhibitory Effects of FA and CF on Rabbit Platelet Aggregation Induced by AA (330 µM), ADP (15 µM) and THR (0.3U/ml)In Vitro.

FA CF
AA
Test range (µg/ml) 101.0-1619.4a 2.3-37.6
Linear range (µg/ml) 101.0-1619.4 2.3-37.6
Regression equation Yb= 53.14x - 1.86 Yc= 58.63x + 0.08
R2 0.984 0.949
IC50(µg/ml) 974.8 ± 97.5 7.1 ± 0.3
ADP
Test range (µg/ml) 202.4-1215.0 19.0-303.2
Linear range (µg/ml) 202.4-1215.0 19.0-303.2
Regression equation Yb = 92.63x - 8.52 Yb= 147.51x + 9.67
R2 0.903 0.995
IC50(µg/ml) 737.9 ± 40.2 276.4 ± 53.4
THR
Test range (µg/ml) 25.2-403.9 19.0-303.2
Linear range (µg/ml) 25.2-403.9 19.0-303.2
Regression equation Yb = 136.39x + 16.66 Yc = 62.03x - 66.61
R2 0.950 0.939
IC50(µg/ml) 244.6 ± 25.6 77.5 ± 23.1

IC50 values were expressed as the mean ±SD and presented as an average of three replicates.
aThe actual tested samples were obtained with serial double dilution through the highest to lowest concentration of samples except FA (202.4, 404.8, 485.8, 809.7 and 1215.0 µg/ml)for ADP-induced platelet aggregation assay.
b Regression equations were expressed as inhibition% vs. concentration (mg/ml).
c Regression equation were as inhibition% vs. the logistic of concentration (µg/ml).