Table 2: Effects of AMC on IFN-γ and IL-10 Levels of Sera of Collagen-Immunized DBA/1 Micea

Treatment IFN-β pg/ml IL-10 pg/ml
27 Days 31 Days 27 Days 31 Days
Mock-immunized mice 4.7±0.3 4.7±0.3 81.6±68.6 139.9±55.1
Collagen-immunized mice
AMC 0 mg/kg 47.3±14.1 148.7±36.8 95.6±51.1 1012.7±118.7
AMC 30 mg/kg 5.3±0.4b 79.3±52.8 86.9±23.0 1034.1±121.9

a AMC at 0 and 30 mg/kg was orally administered to collagen-immunized mice.
On days 27 and 31 after priming, sera were prepared from 5 mice in each group.
The IL-10 and IFN-γ levels in the sera are expressed as the mean±SEM.
b p<0.05 vs. AMC at 0 mg/kg by Student’s t-test.