Table 1: Cytotoxic activity of compounds 1 and 2 against human cancer lines determined by MTT reduction assay.
| Sample |
IC50 (μM) |
| LS-180 |
MCF-7 |
MOLT-4 |
| Compound 1
|
42.6 ± 3.2 |
44.0 ± 6.4 |
39.4 ± 4.8 |
| Compound 2
|
42.8 ± 2.1 |
35.2 ± 3.6 |
28.4 ± 3.7 |
| Cisplatin |
5.9 ± 2.4 |
12.6 ± 5.8 |
3.1 ± 0.8 |
The results are presented as mean ± S.E.M. of 3-4 experiments.