Table 1:
Cytotoxic activity of compounds 1 and 2 against human cancer lines determined by MTT reduction assay.
Sample
IC
50
(μM)
LS-180
MCF-7
MOLT-4
Compound
1
42.6 ± 3.2
44.0 ± 6.4
39.4 ± 4.8
Compound
2
42.8 ± 2.1
35.2 ± 3.6
28.4 ± 3.7
Cisplatin
5.9 ± 2.4
12.6 ± 5.8
3.1 ± 0.8
The results are presented as mean ± S.E.M. of 3-4 experiments.