Fig. (6) Modulatory effect of the antioxidant compounds on SOD activity upon PQ exposure. Both males (A) and females (B) showed a significant decrease in the activity of Cu/Zn-SOD when exposed to multiple dose of PQ while the activity of Mn-SOD was markedly decreased in males (C) and females (D). Antioxidant compounds (4-Hydroxyisophthalic acid-DHA-I, Nicotinamide-NA, Ellagic Acid-EA, Quercetin-Que) prevented the PQ-induced changes in SOD activity. Values are mean±S.E. and bars denoted by identical lowercase alphabets (a–c) indicate no significant difference, whereas, values denoted by different alphabets indicate a statistically significant difference (p<0.05).