Table 2: Summary of biochemical and biomechanical parameters of the generated cartilage-carrier-constructs (1.) alginate gel: w/o GF, cartilage formation: IGF-I; (2.) alginate gel: w/o GF, cartilage formation: w/o GF; (5.) alginate gel: IGF-I &TGF-β1, cartilage formation: IGF-I; (6.) alginate gel: IGF-I &TGF-β1, cartilage formation: w/o GF; condition 3. and 4. not shown
Condition |
1. |
2. |
5. |
6. |
Height [mm] |
1.07±0.13 |
0.44±0.04 |
1.24±0.01 |
1.47±0.02 |
Wet weight [mg] |
56.28±15.0 |
24.68±3.64 |
76.89±13.0 |
44.8±7.51 |
Young’s Modulus [MPa] |
0.0098±0.003 |
0.0064±0.001 |
0.0357±0.001 |
0.0595±0.013 |
DNA [µg/mgcartilage] |
0.174±0.015 |
0.338±0.125 |
0.180±0.023 |
0.286±0.018 |
GAG [µg/mgcartilage] |
9.78±1.27 |
8.35±1.58 |
20.56±2.12 |
21.85±2.84 |
GAG/DNA [µg/µg] |
56.62±6.63 |
26.57±6.97 |
116.09±15.43 |
76.88±8.57 |