Table 4: Advantages and disadvantages of some casting materials used in biomodels.

Advantages Disadvantages
PDMS Nontoxicity;
Biocompatibility;
Gas permeability;
Simple fabrication process;
Good optical transparency; Durability;
Elasticity;
Capable of sustaining a variety of cell types;
Inert.
Can absorb small hydrophobic molecules;
Evaporation of water vapor is hard to control;
Hydrophobic nature.
PMMA Economic;
Biocompatibility;
Ease of processing.
Rigid;
Can undergo thermal degradation and thermal oxidative degradation in the presence of oxygen.
Glass Good optical transparency;
Excellent roughness;
Inert.
Difficult to reproduce the desired geometry;
Rigid.