Fig. (2) photomicrograph showing healing of a bony defect grafted with Bio-Oss® Collagen on day 14. New bone (N) can be seen near the margins of the defect. H = host bone. Some Bio-Oss® granules (B) remained at the centre of the bony defect (periodic acid-Schiff stain, original magnification ×40). Image inside box was enlarged in Fig. (3).