Table 4: Classification of patients by demographics, clinical and biochemical data for all patients and females only (males too few for subgroup analysis).

Variable (ALL) N=152 Frequency Reference Ranges
Below normal Elevated Normal -
Demographics (N=152) n(%) n(%) n(%) -
BMI (kg/m2) 10 (7) 56 (37) 86 (56) 18.6-24.9
SBP (mmHg) N/A 48 (32) 104 (68) ≥130
DBP (mmHg)l2 N/A 47 (31) 105 (69) ≥85
ART History, N=152 - Naïve Experienced -
Frequency/n(%) N/A 28 (18) 124 (82) N/A
Clinical data (N=152) n(%) n(%) n(%) -
Nadir CD4 (cells/mm3) 146 (96) N/A 6 (4) >500
CD4 at time of study (cells/mm3) 49 (32) N/A 103 (68) >500
Viral load (counts per mL) N/A 14 (9%) 138 (91) <1000
Lipids (N=152) n(%) n(%) n(%) -
LDL-C (mmol/L) N/A 48 (32) 104 (68) >2.59
TC (mmol/L) N/A 8 (6) 144 (94) >5.17
HDL-C (mmol/L) 91 (60) N/A 61 (40) <1.03Males
<1.29 Females
TC/HDL-C ratio N/A 38 (25) 114 (75) >4.5
Inflammatory Markers n(%) n(%) n(%) -
IL10 (pg/ml) N=152 N/A 60 (39) 92 (61) 0.4–2.0 [23, 25, 26]
TNFα (pg/ml) N=152 N/A 6 (4) 146 (96) 0.0–32.5 [25, 26]
hsCRP (mg/dL) N*=65 N/A 58 (38) 94 (62) 0-3
Variable (FEMALES ONLY) N=113 Frequency Reference Ranges
- Below normal Elevated Normal -
Demographics (N=113) n(%) n(%) n(%) -
BMI (kg/m2) 3 (3) 49 (43) 61 (54) 18.6-24.9
SBP (mmHg) N/A 34 (30) 79(70) ≥130
DBP (mmHg) N/A 34 (30) 79 (70) ≥85
ART History (N=113) - Naïve Experienced -
Frequency/n(%) N/A 19 (17) 94 (83) -
Clinical Data (N=113) n(%) n(%) n(%) -
Nadir CD4 (cells/mm3) 90 (80) N/A 23 (20) >500
CD4 at time of study (cells/mm3) 23 (20) N/A 90 (80) >500
Viral load (counts per mL) N/A 9 (8) 104 (92) <1000
Lipids (N=113) n(%) n(%) n(%) -
LDL-C (mmol/L) N/A 47 (42) 66 (58) >2.59
TC (mmol/L) N/A 7 (6) 106 (94) >5.17
HDL-C (mmol/L) 72 (64) N/A 41 (36) <1.03Males
<1.29 Females
TC/HDL-C ratio N/A 24 (21) 89 (79) >4.5
Inflammatory Markers n(%) n(%) n(%) -
IL10 (pg/ml) [N=113] N/A 47(42) 66 (58) 0.4–2.0 [23, 25, 26]
TNFα (pg/ml) [N=113] N/A 6 (5) 107 (95) 0.0–32.5 [25, 26]
hsCRP (mg/dL) [N*=43] N/A 15 (35) 28 (65) 0-3

N, total number of study participants; N*, fewer participants; n, number of study participants per sub-group; TC, total cholesterol; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; IL-10, interleukin 10; TNF-α. tumour necrosis factor-alpha; hsCRP, highly sensitive C reactive protein