Table 7: Correlation analysis between inflammatory parameters and classical cardiovascular risk markers in HIV infected individuals; Correlation analysis was done using bivariate regression analysis.
Y Variables
Inflammatory Marker |
X Variables
Lipids |
R2
|
P-value |
| TNF-α (pg/ml) vs. |
TC |
0.0004 |
0.807 |
| - |
HDL-C |
0.004 |
0.441 |
| - |
LDL-C |
0.012 |
0.181 |
| - |
TC/HDL-C |
0.0008 |
0.731 |
| IL-10 (pg/ml) vs. |
TC |
0.026 |
0.048* |
| - |
HDL-C |
0.005 |
0.386 |
| - |
LDL-C |
0.004 |
0.450 |
| - |
TC/HDL-C |
0.0008 |
0.726 |
| TNF-α/IL-10 vs. |
TC |
0.008 |
0.281 |
| - |
HDL-C |
0.006 |
0.334 |
| - |
LDL-C |
0.003 |
0.50 |
| - |
TC/HDL-C |
0.0000 |
0.963 |
| hsCRP (mg/dL) vs. |
TC |
0.022 |
0.243 |
| - |
HDL-C |
0.006 |
0.529 |
| - |
LDL-C |
0.002 |
0.733 |
| - |
TC/HDL-C |
0.004 |
0.621 |
IL-10, interleukin 10; TNF-α, tumour necrosis factor-alpha; hsCRP, highly sensitive C reactive protein; TC, total cholesterol; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; IL-10, interleukin 10; TNF-α, tumour necrosis factor-alpha; hsCRP, highly sensitive C reactive protein; BMI, body mass index; R2 = coefficient of determination, Starred P-value* designates significant P <0.05;where β= 0.2 and α=0.05 at 95% CI