Table 1: Methods for determining protease specificity means excellent, “○” means good, “” means fair and “×” means poor.

	MEROPS database	Photometric or Fluorometric assay	FRET assay	Proteome-based method	Biotin-labeled substrate
Sensitivity	-	○	○	○	○
Specificity		○			○
Cost			×	×	△
Easily		○	○	×	○
Crude sample	-	×	×	×
Activity	×				×