Fig. (4) Domain structure and sequence homology of Sec23a proteins. (A) Schematic representation of the structural domains of Sec23a (B) Protein multiple alignment obtained by HomoloGene (https://www.ncbi.nlm.nih.gov/homologene) of Sec23a proteins derived from various species. Conserved Cys 432 and Cys 449 are highlighted in red.