Table 2: PON1 enzyme activity in association with promoter region polymorphism in Alzheimer’s patients and control group.
Enzymes Activity (IU/A) |
Genotypes (Alzheimer patients) |
Genotypes (control) |
|
CC CT TT |
CC CT TT |
Paraoxonase |
45.42* |
27.20* |
13.9*1 |
76.44 |
43.07 |
37.0 |
Arylesterase |
41.0* |
25.81* |
18.06* |
77.56 |
44.45 |
29.66 |
*P< 0.001 (Data are shown as the median, examined by the Mann-Whitney test).
(IU/L= 1 international unit of enzyme activity is explained as enzyme catalyzes the reaction.
rate of 1 μmol per minute in an assay system).