Table 2: Serum biochemistry parameters in mice relative to age and genotype. Retro-orbital collection method.

Plasma Analytes C57Black 3m C57Black 8m ApoE-/- 3m ApoE-/- 8 m
Male (n=6) Male (n=6) Male (n=6) Male (n=6)
Total cholesterol (mmol/l) 2.96±0.57 3.04±0.27 12.85±1.07 19.82±1.25
Triglycerides (mmol/l) 0.97±0.07 0.94±0.11 0.95±0.09 1.08±0.09
AST (u/1) 173.8±56.7 150.3±68.8 182.2±83.1 104.8±45.8
ALT (u/1) 65.0±11.4 63.8±27.0 72.6±19.7 43.1±15.9
Protein (g/l) 46.5±4.5 45.8±2.7 46.0±2.4 47.4±2.5
Albumin (g/l) 28.4±2.0 26.9±2.0 29.4±1.4 28.3±2.4
Creatinine (mmol/l) 34.0±5.0 26.9±2.0 27.0±5.0 29.4±5.0
Urea (mmol/l) 7.6±1.7 8.5±1.1 7.9±1.2 7.3±0.8
Ca (mmol/l) 2.21±0.17 2.29±0.45 2.19±0.18 2.1±0.14
Cl (mmol/l) 124.0±6.0 120.0±4.0 121.0±4.0 124.0±5.0
P (mmol/l) 3.08±0.5 3.26±0.37 2.96±0.55 2.99±0.47