| Metacore Pathway Maps | Genes in Network | p value |
|---|---|---|
| Cytoskeleton remodeling |
MELC, MRLC, MyHC, DOCK1, SMAD3, Rac1, VEGF-A, Tcf(Lef), eIF4G2, SOS, PI3K cat class IA, LIMK2, TGFβR II, Collagen IV, Nucleolin, EK3(MAP2K3), p38, MAPK, PTEN, Actin cytoskeletal, MLCP (cat) |
3.699E-07 |
| Cytoskeleton remodeling by TGF and WNT |
MELC, MRLC, DOCK1, SMAD3, Axin, Rac1, VEGF-A, TCF7L2 (TCF4), Tcf(Lef), Dsh, SOS, PI3K cat class IA, LIMK2, TGFβR II, Collagen IV, WNT, Nucleolin, MMP-7, MEK3(MAP2K3), p38 MAPK, Actin cytoskeletal, Actin |
4.728E-07 |
|
BMP 7 in brown adipocyte differentiation |
CIDE-A, COL5A1, UCP1, TrkC, PPARGC1 (PGC1-alpha), EDNRA, Cytochrome c, DLK, BMPR1A, PPAR-gamma, WNT10A, ELOVL3, SERPINA3 (ACT) |
1.219E-06 |
| Cytoskeleton remodeling by Actin cytoskeletal |
MELC, Myosin II, MRLC, MyHC, Rac1, LIMK2, Actin, MLCP (cat), actin cytoskeleton by Rho GTPases CDO1, Rac1, PP1-cat, SOS, PI3K cat class IA, |
1.239E-05 |
| Transcription by CREB Pathway |
Galpha(s)-specific amine GPCRs, LDHA, IGF-1 receptor, G-protein alpha-s, Calmodulin, MEK3, p38 MAPK, Shc |
2.056E-05 |
| AVP in regulation of Aquaporin 2 & renal water reabsorption |
Myosin II, cAMP-GEFI, MRLC, Non-muscle myosin IIA, MyHC, VAMP3, G-protein alpha-s, Calmodulin, Adenylate cyclase type VI, Adenylate cyclase type III, Actin cytoskeletal, ACTB, V2 receptor |
2.604E-05 |
| Regulation of GSK3 β in bipolar disorder |
TrkC, Axin, PP2A regulatory, PP1-cat, Dsh, DVL-1, SOS, WNT, TrkA, IL-1 beta, Shc, Neutral sphingomyelinase |
5.128E-05 |
| Cell cycle |
Tubulin alpha, Tubulin (in microtubules), Aurora-A, KNSL1, CDC20, Dynein 1, cytoplasmic, Aurora-B, ZW10, RCC1, DCTN2 |
5.386E-05 |
|
Integrin mediated cell adhesion & migration |
MELC, MRLC, MyHC, DOCK1, RASGRF1, Rac1, p190RhoGAP, LIMK2, Collagen IV, Zyxin, Actin cytoskeletal, MLCP (cat) |
8.071E-05 |
| Immune response by CD28 signaling |
LAT, PIP5KI, Calcineurin A (catalytic), ZAP70, NF-AT, Rac1, PI3K cat class IA, CD86, Calmodulin, I-kB, Bcl-XL, p38 MAPK, Lck |
9.403E-05 |