Table 4: The generation of biological networks with the shortest paths algorithm and relative saturation of networks with canonical pathways.

Network Name Processes Size Pathway P Value z Score g Score
TRAF6, MyD88, I-kB, NIK(MAP3K14), MEK3(MAP2K3) MyD88-dependent toll-like receptor signaling pathway (55.8%), toll-like receptor TLR6:TLR2 signaling pathway (53.8%), toll-like receptor TLR1:TLR2 signaling pathway (53.8%), toll-like receptor 2 signaling pathway (53.8%), toll-like receptor 4 signaling pathway (55.8%) 59 184 4.19e-09 9.61 239.61
TCF7L2 (TCF4), Dsh, Tcf(Lef), Axin, WNT Wnt signaling pathway (58.0%), regulation of Wnt signaling pathway (58.0%), canonical Wnt signaling pathway (44.0%), regulation of canonical Wnt signaling pathway (52.0%), positive regulation of signal transduction (76.0%) 50 98 1.19e-14 14.09 136.59
ESR2, NFYA, CDC25A, SMAD3, TGF-β RII negative regulation of transforming growth factor beta receptor signaling pathway (18.4%), N-acetylglucosamine metabolic process (12.2%), cellular response to endogenous stimulus (42.9%), regulation of transforming growth factor beta receptor signaling pathway (18.4%), response to endogenous stimulus (49.0%) 50 34 3.67e-22 19.26 61.76