Fig. (3) Proposed antioxidant action of pyridoxine in human erythrocytes. Pyridoxine acts by neutralizing free radicals to prevent the oxidation of proteins and phospholipids of the erythrocyte membrane. Pyridoxine, when converted to a free radical, could be regenerated with vitamin C or glutathione. X: proteins or phospholipids. X^• and R^•: free radical. GSH: reduced glutathione. GS-SG: oxidized glutathione. Px: pyridoxine. Px^•: free radical of pyridoxine. Vit C_ox: Oxidized vitamin C. Vit C_red: Reduced vitamin C.