Table 1: Kinetic and affinity constants for the interactions studied in this report.

Proteins Ligands ka=kon
[M-1S-1]
kd=koff
[S-1]
KD= kd/ka
[M]
eL42 p53 7,18×103 8,78×10-5 1,22×10-8
eL42 PLP 9,72 2,67×10-3 2,75×10-4
eL42 PLP-treated p53 2,36×103 2,55×10-4 1,08×10-7
eL42 Mdm2 [1-350] 180 1,28×10-3 7,09×10-6
Mdm2 [1-350] p53 429 9,5×10-4 2,21×10-6