Table 2: Optimal Values of the Coefficients xi to be Used to Compute the p_cones Values (Equation 2)

Method	x
DISEMBL_hot_loops	-0.101
DISEMBL_loops	0.377
DISEMBL_remark465	-0.172
DISOPRED	0.048
DRIPRED	0.096
FOLDINDEX	0.262
GLOBPLOT_B	-0.199
GLOBPLOR_r	0.162
IUPRED_L	0.041
IUPRED_S	-0.126
PRELINK	0.078
RONN	0.141