| Cell-Type | Pathway | KEGG Pathway Code | # Genes Gene | Targets | p-Value |
|---|---|---|---|---|---|
| A549 | Ribosome | hsa03010 | 4 | RPL35 RPL3L RPS5 RPS6 | 0.002 |
| Small cell lung cancer | hsa05222 | 8 | AKT3 CCNE1 LAMA5 AMB3 NFKB2 PTK2 RELA RXRB | 0.028 | |
| gamma-Hexachlorocyclohexane degradation | hsa00361 | 9 | ACP5 ACP6 ACPP ALPI ALPL ALPPL2 DHRS2 PON1 PON2 | 0.035 | |
| TGF-beta signaling pathway | hsa04350 | 9 | ACVR2B COMP ID3 MAPK3 NOG TGFB1 THBS4 TNF ZFYVE9 | 0.037 | |
| HFL-1 | Cell Communication | hsa01430 | 24 | CHAD COL11A2 COL1A1 COL6A1 COL6A2 COMP ITGB4 KRT14 KRT15 KRT17 KRT23 KRT37 KRT39 KRT5 KRT71 KRT76 KRT82 KRT9 LAMA1 LAMA5 LAMB3 LAMB4 NES TNC | 0.003 |
| Phosphatidylinositol signaling system | hsa04070 | 14 | CALML3 CDIPT DGKA INPP5E ITPKA ITPR3 PI4KB PIB5PA PIK3CA PIK3CD PIP5K1B PLCG2 PLCZ1 PRKCG | 0.011 | |
| Lysine degradation | hsa00310 | 9 | DLST ECHS1 EHMT2 HADHA NSD1 OGDH OGDHL PLOD1 PLOD3 | 0.013 | |
| Inositol phosphate metabolism | hsa00562 | 10 | INPP5E ITPKA MIOX PI4KB PIB5PA PIK3CA PIK3CD PIP5K1B PLCG2 PLCZ1 | 0.022 | |
| Glycan structures - biosynthesis 1 | hsa01030 | 4 | ALG12 B4GALT3 CHPF ST3GAL2 | 0.023 | |
| Focal adhesion | hsa04510 | 28 | ACTN1 BAD BCAR1 CHAD COL11A2 COL1A1 COL6A1 COL6A2 COMP FLNA ILK ITGA2B ITGB4 LAMA1 LAMA5 LAMB3 LAMB4 MYL2 MYL9 MYLK2 MYLPF PIK3CA PIK3CD PPP1CA PRKCG RAC3 TLN1 TNC | 0.031 | |
| Leukocyte transendothelial mi-gration | hsa04670 | 18 | ACTN1 BCAR1 CD99 CLDN15 CLDN4 CYBA MAPK12 MAPK13 MMP9 MYL2 MYL9 MYLPF NCF1 PIK3CA PIK3CD PLCG2 PRKCG RAPGEF3 | 0.033 | |
| Ribosome | hsa03010 | 2 | RPL3L RPS11 | 0.035 | |
| ECM-receptor interaction | hsa04512 | 14 | AGRN CHAD COL11A2 COL1A1 COL6A1 COL6A2 ITGA2B ITGB4 LAMA1 LAMA5 LAMB3 LAMB4 SV2A TNC | 0.041 | |
| THP-1 | Keratan sulfate biosynthesis | hsa00533 | 4 | ST3GAL3 FUT8 B4GALT2 B4GALT3 | 0.000 |
| Hematopoietic cell lineage | hsa04640 | 7 | CD33 CD1A CD38 CD34 IL4R ITGA5 HLA-DRB5 | 0.024 | |
| PPAR signaling pathway | hsa03320 | 6 | APOC3 RXRB APOA5 APOA2 FABP3 ACOX3 | 0.039 |