Fig. (1) Multiple sequence alignment of NDK proteins from diverse bacterial genera (Invariant amino acid residues HGSD is highlighted and active site H is indicated in bold letter). Multiple alignments were carried out using clustalW (http://www.ebi.ac.uk/clustalw). EcN:NDK from Escherichia coli, PaN: NDK from Pseudomonas aeruginosa, MxN: NDK from Myxococcus xanthus, MlN: NDK from Mycobacterium leprae, MtN: NDK from Mycobacterium tuberculosis (H37Rv), MsN: NDK from Mycobacterium smegmatis (mc²155), DdN: NDK from Dictyostelium discoideum.