Table 4: Available Laboratory Test to Measure HDL Function

Assays of HDL function

Cholesterol Efflux and Reverse
Cholesterol transport
Cellular cholesterol efflux ex vivo.
Macrophage-specific RCT in vivo
Centripetal cholesterol flux estimated from peripheral synthesis and uptake
Mass fecal steroid excretion
Kinetic modeling of cholesterol efflux from tissues in vivo by isotope dilution.

Indexes of anti-Inflammatory activity
Endothelial adhesion molecule expression
Monocyte chemotaxis

Indexes of antioxidant activity
HDL-associated enzymes
Oxidized LDL and PL
NO Production and Endothelial Function
Metrics of Antiplatelet and Antithrombotic Activity