Fig. (3) Simplified diagrams indicating the
medicinal properties of non-insulin diabetes-treatments are shown.
Representative drugs in a group are also presented. Note that some
critical drugs have been omitted for clarity.Annotated abbreviations
used here;AGI: α-Glucosidase inhibitorsDPP4i: Dipeptidyl-peptidase-4 inhibitorsGLP: Glucagon-like peptide-1 agonistsMEG: MeglitinidesMET: MetforminSU: SulfonylureaTZD: ThiazolidinedioneSIRT1: a member of the sirtuins, a distinct class of trichostatin
A-insensitive lysyl-deacetylases