Table 1: List of the sixty-three Nrf2 regulating genes in human from literature and database mining.

Gene Symbol Gene ID Gene Description
TP53 7157 tumor protein p53
BRCA1 672 DNA repair associated
AKT1 207 AKT serine/threonine kinase 1
PPARG 5468 Peroxisome proliferator-activated receptor gamma
PTEN 5728 Phosphatase and tensin homolog
CDH1 999 Cadherin 1
MYC 4609 v-myc avian myelocytomatosis viral oncogene
CDKN1A 1026 Cyclin-dependent kinase inhibitor 1A
CDH1 999 cadherin 1
PIK3CA 5290 Phosphatidylinositol-4, 5-bisphosphate 3-kinase catalytic alpha
HMOX1 3162 heme oxygenase 1
RB1 614041 RB transcriptional corepressor 1
NFE2L2 4780 Nuclear factor, erythroid 2 like 2
GSK3B 2932 Glycogen synthase kinase 3 beta
JUN 3725 Jun proto-oncogene, AP-1 transcription factor
AHR 196 aryl hydrocarbon receptor
PRKCA 5578 Protein kinase C alpha
HDAC1 3065 Histone deacetylase 1
UBC 7316 Ubiquitin C
CREBBP 1387 CREB binding protein
PRKCD 5580 Protein kinase C delta
NQO1 1728 NAD(P)H Quinone dehydrogenase 1
FBXW11 23291 F-box and WD repeat domain containing 11
SQSTM1 8878 Sequestosome 1
SUMO1 7341 Small ubiquitin-like modifier 1
HDAC2 3066 Histone deacetylase 2
SMARCA4 6597 SWI/SNF related, matrix associated, a regulator of chromatin
MAP2K1 5604 Mitogen-activated protein kinase 1
HDAC3 8841 Histone deacetylase 3
YY1 7528 YY1 transcription factor
BTRC 8945 Beta-transducin repeat containing E3 ubiquitin protein ligase
CASP3 836 Caspase 3
KEAP1 9817 kelch-like ECH associated protein 1
CLTC 1213 Clathrin heavy chain
ATF4 468 Activating transcription factors 4
EIF2AK3 9451 eukaryotic translation initiation factor 2 alpha kinase 3
MAFK 7975 MAF bZIP transcription factor K
MAPK9 10155 Tripartite motif containing 28
TRIM28 5598 Mitogen-activated protein kinase 7
GADD45GIP1 90480 GADD45G interacting protein 1
CUL3 6613 Small ubiquitin-like modifier 2
SUMO2 5605 Mitogen-activated protein kinase 2
MAP2K2 5583 Protein kinase C eta
PRKCH 7832 BTG anti-proliferation factor 2
BTG2 6478 Siah E3 ubiquitin protein ligase 2
SIAH2 571 BTB domain and CNC homolog 1
BACH1 6047 Ring finger protein 4
RNF4 6942 Transcription factor 20
COPS7A 50813 COP9 signalosome subunit 7A
CASP1
ENC1
834
8507
Caspase 1
ectodermal-neural cortex 1