Bioinformatics Based Understanding of Effect of Mutations in the Human β Tubulin Outside Drug Binding Sites and its Significance in Drug Resistance

Fig. (2) Hydrogen bonding pattern analysis before and after the substitution of amino acids in human β tubulin (a) wild type197, (b) wildtype 306 (c) wildtype 350 (d)mut1(e)mut2(f)mut3.